When it comes to hepatitis C treatment, a medical approach to eliminating the hepatitis C virus from the body using antiviral drugs. Also known as HCV therapy, it’s no longer the long, brutal process it was two decades ago. Today, over 95% of people who start treatment are cured — often in just 8 to 12 weeks. That’s not a guess. That’s what real-world data from clinics and health agencies show.
The game-changer? direct-acting antivirals, a class of medications that target specific parts of the hepatitis C virus to stop it from multiplying. These aren’t old-school interferon shots with side effects like fatigue, depression, and fever. These are oral pills you take once a day. They work fast, have few side effects, and don’t require blood tests every week. sofosbuvir, one of the first and most widely used direct-acting antivirals, often combined with other drugs to boost effectiveness started this revolution. Now, newer combinations like glecaprevir/pibrentasvir and sofosbuvir/velpatasvir have taken over because they work against all major strains of the virus — what doctors call pan-genotypic therapy, treatments effective across all hepatitis C genotypes without needing to test which one you have first.
You don’t need to know your genotype anymore. You don’t need to be a liver specialist to get treated. Primary care doctors can manage it now. Even people with cirrhosis or HIV co-infection can be cured. The big shift? It’s not about managing hepatitis C anymore — it’s about eliminating it. That’s why global health groups are pushing for eradication by 2030. The tools are here. The challenge now is access, cost, and awareness.
What’s next? Shorter treatments — some trials are testing just 4 weeks. New drugs that work when others fail. Cheaper versions for low-income countries. And more focus on finding people who don’t even know they’re infected. The posts below cover all of this: how today’s treatments compare, what’s coming after sofosbuvir, how pricing affects who gets cured, and why some people still fall through the cracks. You’ll find real, practical info — no fluff, no hype. Just what you need to understand your options or help someone else navigate them.
Velpatasvir, combined with sofosbuvir, cures over 95% of hepatitis C cases in just 8-12 weeks. Learn how this breakthrough drug works, who it helps, and what’s new in 2025.
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